Cancer is the most prominent non-communicable disease, which is responsible for the high mortality and morbidity worldwide in every age group and gender. The most common cancer in India is breast cancer, followed by lung and head & neck cancer. The incidence and prevalence of all cancer are rising continuously even after the advancements in medical technology, the discovery of novel chemotherapy, and new surgical protocols. The treatment protocol for cancer involves surgical excision of the tumor, radiotherapy, or chemotherapy. Surgical removal of the tumor remains the primary choice of treatment which could be followed by flap reconstruction for functional rehabilitation. Radiotherapy is introduced in preoperative cases when the tumor size is large and needs to be shrunk to make it feasible to be removed by the surgery. Radiotherapy in post-operative cases is given if the surgical site shows positivity for residual tumor cells. Chemotherapy is given by the surgical removal of the tumor, and radiotherapy treatment is not possible.